NUDT2 antibody
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Description
Asymmetrically hydrolyzes Ap4A to yield AMP and ATP. Plays a major role in maintaining homeostasis.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | nudix(nucleoside diphosphate linked moiety X)-type motif 2 (NUDT2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 17kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P50583 |
| Gene ID | 318 |
| Alias | Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical],Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase (Ap4A hydrolase, Ap4Aase, Diadenosine tetraphosphatase),Nucleoside diphosphate-linked moiety X motif 2 (Nudix motif 2),NUDT2,APAH1 |
| Background | Antibody anti-NUDT2 |
| Status | RUO |
| Note | Mol. Weight 17 kDa |
Descripción
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NUDT2 Antibody is a Rabbit Polyclonal antibody against NUDT2. This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified.
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