NUAK2 antibody
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935106861
info@markelab.com
name
NUAK2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05886
tested applications
ELISA, WB, IHC, IF
Description
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | NUAK family, SNF1-like kinase, 2 (NUAK2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 70 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9H093 |
| Gene ID | 81788 |
| Alias | NUAK family SNF1-like kinase 2,Omphalocele kinase 2,SNF1/AMP kinase-related kinase (SNARK),NUAK2,OMPHK2,SNARK |
| Background | Antibody anti-NUAK2 |
| Status | RUO |
| Note | Mol. Weight 70 kDa |
Descripción
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NUAK2 antibody
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.
Ver Producto