NSUN2 antibody

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935106861
info@markelab.com
name
NSUN2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05870
tested applications
ELISA, WB, IHC, IF
Description
RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine(m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. May act downstream of Myc to regulate epidermal cell growth and proliferation. Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | NOL1/NOP2/Sun domain family, member 2 (NSUN2) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 90-100 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, IF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q08J23 |
Gene ID | 54888 |
Alias | RNA cytosine C(5)-methyltransferase NSUN2,Myc-induced SUN domain-containing protein (Misu),NOL1/NOP2/Sun domain family member 2,Substrate of AIM1/Aurora kinase B,mRNA cytosine C(5)-methyltransferase,tRNA cytosine C(5)-methyltransferase,tRNA methyltransferase 4 homolog (hTrm4),NSUN2,SAKI,TRM4 |
Background | Antibody anti-NSUN2 |
Status | RUO |
Note | Mol. Weight 90-100 kDa |
Descripción
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NSUN2 antibody
RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine(m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. May act downstream of Myc to regulate epidermal cell growth and proliferation. Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.
Ver Producto