NSUN2 antibody

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935106861
info@markelab.com
name
NSUN2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05870
tested applications
ELISA, WB, IHC, IF

Description

RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine(m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. May act downstream of Myc to regulate epidermal cell growth and proliferation. Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
NOL1/NOP2/Sun domain family, member 2 (NSUN2)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
90-100 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q08J23
Gene ID
54888
Alias
RNA cytosine C(5)-methyltransferase NSUN2,Myc-induced SUN domain-containing protein (Misu),NOL1/NOP2/Sun domain family member 2,Substrate of AIM1/Aurora kinase B,mRNA cytosine C(5)-methyltransferase,tRNA cytosine C(5)-methyltransferase,tRNA methyltransferase 4 homolog (hTrm4),NSUN2,SAKI,TRM4
Background
Antibody anti-NSUN2
Status
RUO
Note
Mol. Weight 90-100 kDa

Descripción

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