NPPB antibody
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Description
NPPB, also known as B-type natriuretic peptide (BNP), is a cardiac hormone that is secreted mainly in the ventricles in response to increased wall stress. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. BNP is a marker of systolic and diastolic dysfunction and a strong predictor of mortality in heart failure patients.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | natriuretic peptide precursor B (NPPB) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 15 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P16860 |
| Gene ID | 4879 |
| Alias | Natriuretic peptides B,Brain natriuretic factor prohormone (preproBNP, proBNP),Gamma-brain natriuretic peptide,Iso-ANP,NT-proBNP Alternative names: NT-pro-BNP,NT-proBNP(1-76),proBNP(3-108),Brain natriuretic peptide 32 (BNP(1-32), BNP-32) Alternative names: Brain natriuretic peptide (BNP),BNP(1-30),BNP(1-29),BNP(1-28),BNP(2-31),BNP(3-32) Alternative names: des-SerPro-BNP,proBNP(79-108),BNP(3-30),BNP(3-29),Brain natriuretic peptide 29 (BNP(4-32)),BNP(4-31),BNP(4-30),BNP(4-29),BNP(4-27),BNP(5-32),BNP(5-31),BNP(5-29),NPPB |
| Background | Antibody anti-NPPB |
| Status | RUO |
| Note | Mol. Weight 15 kDa |
Descripción
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NPPB antibody
NPPB, also known as B-type natriuretic peptide (BNP), is a cardiac hormone that is secreted mainly in the ventricles in response to increased wall stress. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. BNP is a marker of systolic and diastolic dysfunction and a strong predictor of mortality in heart failure patients.
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Natriuretic Peptides B (NPPB) Antibody
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