NPL antibody
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935106861
info@markelab.com
name
NPL antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05820
tested applications
ELISA, WB, IF
Description
Catalyzes the cleavage of N-acetylneuraminic acid(sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid(Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | N-acetylneuraminate pyruvate lyase(dihydrodipicolinate synthase) (NPL) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 35 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BXD5 |
| Gene ID | 80896 |
| Alias | N-acetylneuraminate lyase (NALase),N-acetylneuraminate pyruvate-lyase,N-acetylneuraminic acid aldolase,Sialate lyase,Sialate-pyruvate lyase,Sialic acid aldolase,Sialic acid lyase,NPL,C1orf13 |
| Background | Antibody anti-NPL |
| Status | RUO |
| Note | Mol. Weight 35 kDa |
Descripción
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NPL antibody
Catalyzes the cleavage of N-acetylneuraminic acid(sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid(Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded(By similarity).
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