IQCB1 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
IQCB1, also known as NPHP5, is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. It has a central coiled-coil region and two calmodulin-binding IQ domains. Localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells, IQCB1 is thought to play a role in ciliary function. Mutations in this gene result in Senior-Loken syndrome type 5, a juvenile disorder characterized by defects in the waste filtering system of the kidney, as well as retinal degradation.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | IQ motif containing B1 (IQCB1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q15051 |
| Alias | IQ calmodulin-binding motif-containing protein 1,Nephrocystin-5,p53 and DNA damage-regulated IQ motif protein (PIQ),IQCB1,KIAA0036,NPHP5 |
| Background | Antibody anti-IQCB1 |
| Status | RUO |
| Note | This product is for research use only. |
Descripción
Related Products
IQCB1 antibody
IQCB1, also known as NPHP5, is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. It has a central coiled-coil region and two calmodulin-binding IQ domains. Localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells, IQCB1 is thought to play a role in ciliary function. Mutations in this gene result in Senior-Loken syndrome type 5, a juvenile disorder characterized by defects in the waste filtering system of the kidney, as well as retinal degradation.
Ver Producto
IQ Motif Containing B1 (IQCB1) Antibody
Rabbit polyclonal antibody against IQCB1 protein. Immunogen region is Internal.
Ver Producto
Human IQ Calmodulin-Binding Motif-Containing Protein 1 (IQCB1) ELISA Kit
Human IQ Calmodulin-Binding Motif-Containing Protein 1 (IQCB1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human NPHP5/IQCB1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver Producto