NPHP3 antibody

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935106861
info@markelab.com
name
NPHP3 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05816
tested applications
ELISA, WB, IF, IHC, IP
Description
Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | nephronophthisis 3(adolescent) (NPHP3) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 145-151 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q7Z494 |
| Gene ID | 27031 |
| Alias | Nephrocystin-3,NPHP3,KIAA2000 |
| Background | Antibody anti-NPHP3 |
| Status | RUO |
| Note | Mol. Weight 145-151 kDa |
Descripción
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NPHP3 antibody
Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.
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Nephrocystin 3 (NPHP3) Antibody
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