NOX4 antibody
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935106861
info@markelab.com
name
NOX4 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05806
tested applications
ELISA, WB, IHC, IP, IF, FC
Description
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | NADPH oxidase 4 (NOX4) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:2000; IP: 1:500-1:2000; IHC: 1:100-1:400; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 60 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP, IF, FC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9NPH5 |
| Gene ID | 50507 |
| Alias | NADPH oxidase 4,Kidney oxidase-1 (KOX-1),Kidney superoxide-producing NADPH oxidase,Renal NAD(P)H-oxidase,NOX4,RENOX |
| Background | Antibody anti-NOX4 |
| Status | RUO |
| Note | Mol. Weight 60 kDa |
Descripción
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NOX4 antibody
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation.
Ver Producto