NLRX1 antibody
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Description
Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH(RIG-like helicase)-MAVS interaction(PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species(PubMed:18219313).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | NLR family member X1 (NLRX1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 110 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q86UT6 |
| Gene ID | 79671 |
| Alias | NLR family member X1,Caterpiller protein 11.3 (CLR11.3),Nucleotide-binding oligomerization domain protein 5,Nucleotide-binding oligomerization domain protein 9,NLRX1,NOD5,NOD9 |
| Background | Antibody anti-NLRX1 |
| Status | RUO |
| Note | Mol. Weight 110 kDa |
Descripción
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