anti- NLRP2 antibody

Name: anti- NLRP2 antibody
Brand: FineTest
SKU: FNab05758
Availability: OnlineOnly

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-NLRP2

proveedor

FineTest

reference

FNab05758

Tested Applications

ELISA, WB, IHC

reactivity

human,mouse

status

RUO

clonality

polyclonal

Descripción

Suppresses TNF-and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.

Características del producto

clonality

polyclonal

reactivity

human,mouse

immunogen target

NLR family, pyrin domain containing 2

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IHC

observerd MW

105-110 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

NLRP2

alias

NALP2, NBS1, PAN1, PYPAF2

uniprot id

https://www.uniprot.org/uniprotkb/Q9NX02

gene id

https://www.ncbi.nlm.nih.gov/gene/55655

note

This product is for research use only.

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