NLRP2 antibody
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935106861
info@markelab.com
name
NLRP2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05758
tested applications
ELISA, WB, IHC
Description
Suppresses TNF-and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | NLR family, pyrin domain containing 2 (NLRP2) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 105-110 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9NX02 |
| Gene ID | 55655 |
| Alias | NACHT, LRR and PYD domains-containing protein 2,Nucleotide-binding site protein 1,PYRIN domain and NACHT domain-containing protein 1,PYRIN-containing APAF1-like protein 2,NLRP2,NALP2,NBS1,PAN1,PYPAF2 |
| Background | Antibody anti-NLRP2 |
| Status | RUO |
| Note | Mol. Weight 105-110 kDa |
Descripción
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