NKX2-2 antibody
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Description
Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter(By similarity).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | NK2 homeobox 2 (NKX2-2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 30 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O95096 |
| Gene ID | 4821 |
| Alias | Homeobox protein Nkx-2.2,Homeobox protein NK-2 homolog B,NKX2-2,NKX2.2,NKX2B |
| Background | Antibody anti-NKX2-2 |
| Status | RUO |
| Note | Mol. Weight 30 kDa |
Descripción
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