NFX1 antibody
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935106861
info@markelab.com
name
NFX1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05715
tested applications
ELISA, WB
Description
Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. Mediates E2-dependent ubiquitination.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | nuclear transcription factor, X-box binding 1 (NFX1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 124kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q12986 |
| Gene ID | 4799 |
| Alias | Transcriptional repressor NF-X1,Nuclear transcription factor, X box-binding protein 1,NFX1,NFX2 |
| Background | Antibody anti-NFX1 |
| Status | RUO |
| Note | Mol. Weight 124 kDa |
Descripción
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