NENF antibody
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935106861
info@markelab.com
name
NENF antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05661
tested applications
ELISA, IHC, WB,IF
Description
Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance(By similarity). Plays a role in the human tumorigenesis(PubMed:22748190).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | neuron derived neurotrophic factor (NENF) |
| Host | Mouse |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:500 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a |
| Clone ID | 7C8 |
| Observed MW | 18 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB,IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UMX5 |
| Gene ID | 29937 |
| Alias | Neudesin,Cell immortalization-related protein 2,Neuron-derived neurotrophic factor,Protein GIG47,Secreted protein of unknown function (SPUF protein),NENF,CIR2,SPUF |
| Background | Antibody anti-NENF |
| Status | RUO |
| Note | Mol. Weight 18 kDa |
Descripción
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NENF antibody
Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance(By similarity). Plays a role in the human tumorigenesis(PubMed:22748190).
Ver Producto