NEDD4L antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | neural precursor cell expressed, developmentally down-regulated 4-like (NEDD4L) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 113 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q96PU5 |
| Gene ID | 23327 |
| Alias | E3 ubiquitin-protein ligase NEDD4-like,HECT-type E3 ubiquitin transferase NED4L,NEDD4.2,Nedd4-2,NEDD4L,KIAA0439,NEDL3 |
| Background | Antibody anti-NEDD4L |
| Status | RUO |
| Note | Mol. Weight 113 kDa |
Descripción
Related Products
NEDD4L antibody
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Ver Producto
Recombinant Human NEDD4L
Ver Producto
E3 Ubiquitin-Protein Ligase NEDD4-Like (NEDD4L) Antibody
NEDD4L Antibody is a Rabbit Polyclonal Antibody against NEDD4L.
Ver Producto