NDC80 antibody

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935106861
info@markelab.com
name
NDC80 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05599
tested applications
ELISA, WB, IHC, IP

Description

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity(PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore(PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules(PubMed:23085020).

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
NDC80 homolog, kinetochore complex component (NDC80)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
76 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
O14777
Gene ID
10403
Alias
Kinetochore protein NDC80 homolog,Highly expressed in cancer protein,Kinetochore protein Hec1 (HsHec1),Kinetochore-associated protein 2,Retinoblastoma-associated protein HEC,NDC80,HEC,HEC1,KNTC2
Background
Antibody anti-NDC80
Status
RUO
Note
Mol. Weight 76 kDa

Descripción

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