Anti-NCR1 antibody

Descripción

The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.

Características del producto

clonality

polyclonal

reactivity

human,mouse

immunogen target

Natural cytotoxicity triggering receptor 1

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IHC, IF

observerd MW

46 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

NCR1

alias

Lymphocyte antigen 94 homolog,LY94,CD335,NKP46,NK-p46,NK cell-activating receptor,Natural killer cell p46-related protein

uniprot id

https://www.uniprot.org/uniprotkb/O76036

gene id

https://www.ncbi.nlm.nih.gov/gene/9437

note

This product is for research use only.

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