NCOR2 antibody

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935106861
info@markelab.com
name
NCOR2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab10069
tested applications
ELISA, IHC

Description

Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center(GC) reactions, mainly through the control of the GC B-cells proliferation and survival.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
nuclear receptor co-repressor 2 (NCOR2)
Host
Rabbit
Reactivity
Human, mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:50-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
180 kDa, 275 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q9Y618
Gene ID
9612
Alias
Nuclear receptor corepressor 2 (N-CoR2),CTG repeat protein 26,SMAP270,Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT),T3 receptor-associating factor (TRAC),Thyroid-, retinoic-acid-receptor-associated corepressor,NCOR2,CTG26
Background
Antibody anti-NCOR2
Status
RUO
Note
Mol. Weight 180 kDa, 275 kDa

Descripción

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Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center(GC) reactions, mainly through the control of the GC B-cells proliferation and survival.

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