anti- MYO7B antibody

Este producto es parte de MYO7 - myosin VII
anti- MYO7B antibody

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935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-MYO7B

proveedor

FineTest

reference

FNab05508

Tested Applications

ELISA, IHC

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. May link the complex to the actin core bundle of microvilli(Probable).


Background

Myosin VIIB (MYO7B) is a motor protein from the myosin family, which is involved in ATP-dependent cellular movements Myosin VIIB, like other myosins, moves along actin filaments, converting chemical energy into mechanical work This motor protein is crucial for cellular processes such as vesicular transport, endocytosis, and cell migration MYO7B plays a specific role in the auditory and visual systems, where it is involved in the function of sensory cells, including the hair cells of the inner ear and photoreceptors in the retina In the inner ear, MYO7B helps maintain the structure and function of hair cells, which are responsible for detecting sound vibrations and balancing signals Disruption in MYO7B function leads to hearing loss and progressive blindness, as seen in Usher syndrome type 2, where both deafness and vision impairment occur due to defects in inner ear and retinal cells

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human,mouse,rat


immunogen target

myosin VIIB


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, IHC


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

IHC: 1:20-1:200


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

MYO7B


alias

Unconventional myosin-VIIb


note

This product is for research use only.


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