MVK antibody
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Description
May be a regulatory site in cholesterol biosynthetic pathway.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | mevalonate kinase (MVK) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 42 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q03426 |
| Gene ID | 4598 |
| Alias | Mevalonate kinase (MK),MVK |
| Background | Antibody anti-MVK |
| Status | RUO |
| Note | Mol. Weight 42 kDa |
Descripción
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Human MVK (Mevalonate kinase) ELISA Kit
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Mevalonate Kinase (MVK) Antibody
MVK Antibody is a Rabbit Polyclonal antibody against MVK. This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene.
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