MTMR6 antibody
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Description
Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | myotubularin related protein 6 (MTMR6) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 64-67 kDa, 72-76 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9Y217 |
| Gene ID | 9107 |
| Alias | Myotubularin-related protein 6,Phosphatidylinositol-3,5-bisphosphate 3-phosphatase,Phosphatidylinositol-3-phosphate phosphatase,MTMR6 |
| Background | Antibody anti-MTMR6 |
| Status | RUO |
| Note | Mol. Weight 64-67 kDa, 72-76 kDa |
Descripción
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MTMR6 antibody
Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells.
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