MRAP2 antibody

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935106861
info@markelab.com
name
MRAP2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05304
tested applications
ELISA, IHC

Description

Modulator of melanocortin receptor 4(MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP(By similarity). May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin(ACTH) to MC2R. May also regulate activity of other melanocortin receptors(MC1R, MC3R and MC5R); however, additional evidences are required in vivo.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
melanocortin 2 receptor accessory protein 2 (MRAP2)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q96G30
Gene ID
112609
Alias
Melanocortin-2 receptor accessory protein 2 (MC2R accessory protein 2),MRAP2,C6orf117
Background
Antibody anti-MRAP2
Status
RUO
Note
This product is for research use only.

Descripción

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