MPRIP antibody
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935106861
info@markelab.com
name
MPRIP antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05296
tested applications
ELISA, WB, IHC, IF, IP
Description
Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | myosin phosphatase Rho interacting protein (MPRIP) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 116-140 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q6WCQ1 |
| Gene ID | 23164 |
| Alias | Myosin phosphatase Rho-interacting protein (M-RIP),Rho-interacting protein 3 (RIP3),p116Rip,MPRIP,KIAA0864,MRIP,RHOIP3 |
| Background | Antibody anti-MPRIP |
| Status | RUO |
| Note | Mol. Weight 116-140 kDa |
Descripción
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