MLKL antibody
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935106861
info@markelab.com
name
MLKL antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05217
tested applications
ELISA, WB
Description
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | mixed lineage kinase domain-like (MLKL) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 54 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8NB16 |
| Gene ID | 197259 |
| Alias | Mixed lineage kinase domain-like protein (hMLKL),MLKL |
| Background | Antibody anti-MLKL |
| Status | RUO |
| Note | Mol. Weight 54 kDa |
Descripción
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MLKL antibody
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Ver Producto