MIF antibody

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935106861
info@markelab.com
name
MIF antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05187
tested applications
ELISA, IHC, WB, IP, IF
Description
Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity(in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | macrophage migration inhibitory factor(glycosylation-inhibiting factor) (MIF) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 12 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, IHC, WB, IP, IF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | P14174 |
Gene ID | 4282 |
Alias | Macrophage migration inhibitory factor (MIF),Glycosylation-inhibiting factor (GIF),L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase,MIF,GLIF,MMIF |
Background | Antibody anti-MIF |
Status | RUO |
Note | Mol. Weight 12 kDa |
Descripción
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MIF antibody
Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity(in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.
Ver Producto