MICALL2 antibody

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Description
Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth(By similarity).
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Product specifications
Category | Primary Antibodies |
Immunogen Target | MICAL-like 2 (MICALL2) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1:500-1:2000 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 109 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q8IY33 |
Gene ID | 79778 |
Alias | MICAL-like protein 2,Junctional Rab13-binding protein,Molecule interacting with CasL-like 2 (MICAL-L2),MICALL2,JRAB |
Background | Antibody anti-MICALL2 |
Status | RUO |
Note | Mol. Weight 109 kDa |
Descripción
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