MICAL1 antibody
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935106861
info@markelab.com
name
MICAL1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05177
tested applications
ELISA, WB, IHC, IP, FC
Description
Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization(Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L; acts by antagonizing STK38 and STK38L activation by MST1/STK4.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | microtubule associated monoxygenase, calponin and LIM domain containing 1 (MICAL1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:1000-1:4000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 120 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP, FC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8TDZ2 |
| Gene ID | 64780 |
| Alias | [F-actin]-monooxygenase MICAL1,Molecule interacting with CasL protein 1 (MICAL-1),NEDD9-interacting protein with calponin homology and LIM domains,MICAL1,MICAL,NICAL |
| Background | Antibody anti-MICAL1 |
| Status | RUO |
| Note | Mol. Weight 120 kDa |
Descripción
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MICAL1 antibody
Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization(Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L; acts by antagonizing STK38 and STK38L activation by MST1/STK4.
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