MGAT5B antibody
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Description
Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine(GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3-and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | mannosyl(alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B (MGAT5B) |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 89-100 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q3V5L5 |
| Gene ID | 146664 |
| Alias | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B,Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B,GlcNAc-T Vb (GNT-Vb, hGnTVb),Mannoside acetylglucosaminyltransferase 5B,N-acetylglucosaminyl-transferase Vb,N-acetylglucosaminyltransferase IX (GNT-IX),MGAT5B,KIAA2008 |
| Background | Antibody anti-MGAT5B |
| Status | RUO |
| Note | Mol. Weight 89-100 kDa |
Descripción
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