MEX3C antibody
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935106861
info@markelab.com
name
MEX3C antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05145
tested applications
ELISA, WB, IHC
Description
E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | mex-3 homolog C(C. elegans) (MEX3C) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 69 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q5U5Q3 |
| Gene ID | 51320 |
| Alias | RNA-binding E3 ubiquitin-protein ligase MEX3C,RING finger and KH domain-containing protein 2,RING finger protein 194,RING-type E3 ubiquitin transferase MEX3C,MEX3C,RKHD2,RNF194 |
| Background | Antibody anti-MEX3C |
| Status | RUO |
| Note | Mol. Weight 69 kDa |
Descripción
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MEX3C antibody
E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.
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