MLPH antibody
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | melanophilin (MLPH) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 1:1000-1:6000; IHC: 1:20-1:200; IF: 1:10-1:100 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a |
| Clone ID | 8B2 |
| Observed MW | 66 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BV36 |
| Alias | Melanophilin,Exophilin-3,Slp homolog lacking C2 domains a (SlaC2-a),Synaptotagmin-like protein 2a,MLPH,SLAC2A |
| Background | Antibody anti-MLPH |
| Status | RUO |
| Note | Mol. Weight 66 kDa |
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MLPH Antibody is a Rabbit Polyclonal antibody against MLPH. This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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