MED15 antibody
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Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | mediator complex subunit 15 (MED15) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 105 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q96RN5 |
| Gene ID | 51586 |
| Alias | Mediator of RNA polymerase II transcription subunit 15,Activator-recruited cofactor 105 kDa component (ARC105),CTG repeat protein 7a,Mediator complex subunit 15,Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein),TPA-inducible gene 1 protein (TIG-1),Trinucleotide repeat-containing gene 7 protein,MED15,ARC105,CTG7A,PCQAP,TIG1,TNRC7 |
| Background | Antibody anti-MED15 |
| Status | RUO |
| Note | Mol. Weight 105 kDa |
Descripción
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