MCRS1 antibody
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Description
Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus(PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues(PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity(PubMed:15044100). Binds to G-quadruplex structures in mRNA(PubMed:16571602). Binds to RNA homopolymer poly(G) and poly(U)(PubMed:16571602).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | microspherule protein 1 (MCRS1) |
| Host | Mouse |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a |
| Clone ID | 5G3 |
| Observed MW | 55 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q96EZ8 |
| Gene ID | 10445 |
| Alias | Microspherule protein 1,58 kDa microspherule protein,Cell cycle-regulated factor p78,INO80 complex subunit J,MCRS2,MCRS1,INO80Q,MSP58 |
| Background | Antibody anti-MCRS1 |
| Status | RUO |
| Note | Mol. Weight 55 kDa |
Descripción
Related Products
MCRS1 antibody
Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus(PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues(PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity(PubMed:15044100). Binds to G-quadruplex structures in mRNA(PubMed:16571602). Binds to RNA homopolymer poly(G) and poly(U)(PubMed:16571602).
Ver ProductoMCRS1 antibody
Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus(PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues(PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity(PubMed:15044100). Binds to G-quadruplex structures in mRNA(PubMed:16571602). Binds to RNA homopolymer poly(G) and poly(U)(PubMed:16571602).
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