MATK antibody
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Description
The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | megakaryocyte-associated tyrosine kinase (MATK) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 55 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P42679 |
| Gene ID | 4145 |
| Alias | Megakaryocyte-associated tyrosine-protein kinase,CSK homologous kinase (CHK),Hematopoietic consensus tyrosine-lacking kinase,Protein kinase HYL,Tyrosine-protein kinase CTK,MATK,CTK,HYL |
| Background | Antibody anti-MATK |
| Status | RUO |
| Note | Mol. Weight 55 kDa |
Descripción
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