MAP3K1 antibody
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Description
MAP3K1, also named as MAPKKK1, MEKK and MEKK1, belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase kinase subfamily. MAP3K1 is a component of a protein kinase signal transduction cascade. MAP3K1 activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. It activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway. It catalyzes the reaction: ATP + a protein = ADP + a phosphoprotein.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | mitogen-activated protein kinase kinase kinase 1 (MAP3K1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 164 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q13233 |
| Gene ID | 4214 |
| Alias | Mitogen-activated protein kinase kinase kinase 1,MAPK/ERK kinase kinase 1 (MEK kinase 1, MEKK 1),MAP3K1,MAPKKK1,MEKK,MEKK1 |
| Background | Antibody anti-MAP3K1 |
| Status | RUO |
| Note | Mol. Weight 164 kDa |
Descripción
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