MAGEA6 antibody

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935106861
info@markelab.com
name
MAGEA6 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04939
tested applications
ELISA, WB, IHC, IF
Description
Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.
Documents del producto
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | melanoma antigen family A, 6 (MAGEA6)  | 
| Host | Rabbit  | 
| Reactivity | Human, Mouse  | 
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200  | 
| Clonality | polyclonal  | 
| Conjugation | Unconjugated  | 
| Isotype | IgG  | 
| Observed MW | 66-70 kDa  | 
| Purity | ≥95% as determined by SDS-PAGE  | 
| Purification | Immunogen affinity purified  | 
| Size 1 | 100µg  | 
| Form | liquid  | 
| Tested Applications | ELISA, WB, IHC, IF  | 
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)  | 
| UniProt ID | P43360  | 
| Gene ID | 4105  | 
| Alias | Melanoma-associated antigen 6,Cancer/testis antigen 1.6 (CT1.6),MAGE-6 antigen,MAGE3B antigen,MAGEA6,MAGE6  | 
| Background | Antibody anti-MAGEA6  | 
| Status | RUO  | 
| Note | Mol. Weight 66-70 kDa  | 
Descripción
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