anti- MAGEA3 antibody

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935106861
info@markelab.com
name
anti- MAGEA3 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04937
tested applications
ELISA, WB, IHC

Description

Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

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Product specifications

CategoryPrimary Antibodies
Immunogen Targetmelanoma antigen family A, 3
HostMouse
Reactivityhuman
Recommended DilutionWB: 1:500-1:2000; IHC: 1:50-1:200
Clonalitymonoclonal
ConjugationUnconjugated
IsotypeIgG2a
Clone ID4E9
Observed MW35-55 kDa
Purity≥95% as determined by SDS-PAGE
PurificationProtein A+G purification
Size 1100µg
Formliquid
Tested ApplicationsELISA, WB, IHC
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt IDP43357
Gene ID4102
AliasAntigen MZ2 D, Cancer/testis antigen 1.3, CT1.3, HIP8, HYPD, MAGE 3 antigen, MAGE3, MAGEA3, MAGE-A3, MAGEA6, melanoma antigen family A, 3, Melanoma associated antigen 3
BackgroundAntibody anti-MAGEA3
StatusRUO
NoteThis product is for research use only.

Descripción

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