MAGEA3 antibody
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935106861
info@markelab.com
name
MAGEA3 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04937
tested applications
ELISA, WB, IHC
Description
Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | melanoma antigen family A, 3 (MAGEA3) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:50-1:200 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a |
| Clone ID | 4E9 |
| Observed MW | 35-55 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P43357 |
| Gene ID | 4102 |
| Alias | Melanoma-associated antigen 3,Antigen MZ2-D,Cancer/testis antigen 1.3 (CT1.3),MAGE-3 antigen,MAGEA3,MAGE3 |
| Background | Antibody anti-MAGEA3 |
| Status | RUO |
| Note | Mol. Weight 35-55 kDa |
Descripción
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MAGEA3 antibody
Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Ver Producto