anti- MAGEA3 antibody

anti- MAGEA3 antibody

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935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-MAGEA3

proveedor

FineTest

reference

FNab04937

Tested Applications

ELISA, WB, IHC

reactivity

human

status

RUO

clonality

monoclonal

Descripción

Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Características del producto

category

Primary Antibodies


clonality

monoclonal


reactivity

human


immunogen target

melanoma antigen family A, 3


host

Mouse


isotype

IgG2a


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB, IHC


observerd MW

35-55 kDa


purity

≥95% as determined by SDS-PAGE


purification

Protein A+G purification


recommended dilution

WB: 1:500-1:2000; IHC: 1:50-1:200


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

MAGEA3


alias

Antigen MZ2 D, Cancer/testis antigen 1.3, CT1.3, HIP8, HYPD, MAGE 3 antigen, MAGE3, MAGEA3, MAGE-A3, MAGEA6, melanoma antigen family A, 3, Melanoma associated antigen 3


note

This product is for research use only.


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