MAGEA1 antibody
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Description
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain(NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | melanoma antigen family A, 1(directs expression of antigen MZ2-E) (MAGEA1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 43kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P43355 |
| Gene ID | 4100 |
| Alias | Melanoma-associated antigen 1,Antigen MZ2-E,Cancer/testis antigen 1.1 (CT1.1),MAGE-1 antigen,MAGEA1,MAGE1,MAGE1A |
| Background | Antibody anti-MAGEA1 |
| Status | RUO |
| Note | Mol. Weight 43 kDa |
Descripción
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Human MAGEA1 (Melanoma-associated antigen 1) ELISA Kit
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MAGEA1 antibody
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
Ver ProductoMAGEA1 antibody
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain(NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Ver Producto