MAEA antibody
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Description
Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | macrophage erythroblast attacher (MAEA) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 42-45 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q7L5Y9 |
| Gene ID | 10296 |
| Alias | E3 ubiquitin-protein transferase MAEA,Cell proliferation-inducing gene 5 protein,Erythroblast macrophage protein,Human lung cancer oncogene 10 protein (HLC-10),Macrophage erythroblast attacher,P44EMLP,MAEA,EMP |
| Background | Antibody anti-MAEA |
| Status | RUO |
| Note | Mol. Weight 42-45 kDa |
Descripción
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