LRSAM1 antibody
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935106861
info@markelab.com
name
LRSAM1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04866
tested applications
ELISA, WB, IHC, IF
Description
E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic(EGF receptors) and exocytic(HIV-1 viral proteins) cargos(PubMed:15256501). Bacterial recognition protein that defends the cytoplasm from invasive pathogens(PubMed:23245322). Localizes to several intracellular bacterial pathogens and generates the bacteria-associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation(xenophagy)(PubMed:23245322, PubMed:25484098).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | leucine rich repeat and sterile alpha motif containing 1 (LRSAM1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 84 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q6UWE0 |
| Gene ID | 90678 |
| Alias | E3 ubiquitin-protein ligase LRSAM1,Leucine-rich repeat and sterile alpha motif-containing protein 1,RING-type E3 ubiquitin transferase LRSAM1,Tsg101-associated ligase (hTAL),LRSAM1,TAL |
| Background | Antibody anti-LRSAM1 |
| Status | RUO |
| Note | Mol. Weight 84 kDa |
Descripción
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