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Precio
Precio a consultar
Probable substrate recognition component of an ECS(Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
LRRC41 is a protein with proposed roles in DNA damage repair and ubiquitin-mediated proteolysis studies suggest it functions as an E3 ubiquitin ligase interacting with other proteins involved in the ubiquitin-proteasome system to regulate protein turnover and cellular stress responses LRRC41 is widely expressed in tissues undergoing high cellular turnover and is particularly enriched in hematopoietic cells where it may influence cell cycle progression and apoptosis its involvement in DNA repair pathways highlights its potential role in maintaining genomic stability and preventing tumorigenesis mutations or altered expression of LRRC41 have been associated with certain cancers and hematological disorders ongoing research is exploring its function in protein quality control and its potential as a therapeutic target in diseases associated with proteostasis and genomic instability further studies are needed to define its exact biological mechanisms and regulatory networks
Primary Antibodies
polyclonal
human,mouse,rat
leucine rich repeat containing 41
Rabbit
IgG
Unconjugated
liquid
ELISA, IHC, WB
80-90 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:2000; IHC: 1:20-1:200
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
LRRC41
LRRC41, MUF1, PP7759
This product is for research use only.
Probable substrate recognition component of an ECS(Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which...
Precio a consultar
Ver másRabbit polyclonal antibody against LRRC41 protein. Immunogen region is Internal.
43.75€ (10 µg)
Ver másLeucine Rich Repeat Containing 41 Antibody is a Rabbit Polyclonal antibody against Leucine Rich Repeat Containing 41.
612.5€ (100 µl)
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