anti- LRRC18 antibody
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935106861
info@markelab.com
name
anti- LRRC18 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04854
tested applications
ELISA, WB, IHC, IP
Descripción del producto
May be involved in the regulation of spermatogenesis and sperm maturation.
Documents del producto
Instrucciones
Data sheet
Especificaciones del producto
| Alias | LRRC18,UNQ9338/PRO34010 |
| Background | Antibody anti-LRRC18 |
| Category | Primary Antibodies |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Form | liquid |
| Gene ID | 474354 |
| Host | Rabbit |
| Immunogen Target | leucine rich repeat containing 18 |
| Isotype | IgG |
| Name | anti- LRRC18 antibody |
| Note | This product is for research use only. |
| Observed MW | 30 kDa |
| Provider | FineTest |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Reactivity | human,mouse |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200 |
| Reference | FNab04854 |
| Size 1 | 100µg |
| Status | RUO |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Tested Applications | ELISA, WB, IHC, IP |
| UniProt ID | Q8N456 |
Descripcion del producto en español
Background en español
LRRC18 is a lesser-characterized member of the LRRC family with suggested roles in immune responses and cellular signaling based on its expression in lymphoid tissues studies have identified LRRC18 as being involved in the regulation of T cell activation and differentiation as it interacts with key signaling pathways associated with immune synapse formation emerging evidence indicates its potential role in modulating inflammatory responses particularly through cytokine release and receptor crosstalk in immune cells its expression pattern suggests involvement in hematopoietic cell function and immune surveillance although its exact biological mechanisms remain to be fully characterized bioinformatics analyses suggest links to signal transduction and membrane trafficking processes LRRC18 may also contribute to tumor immunology by modulating immune cell infiltration and activity within the tumor microenvironment further studies are needed to define its interactions and assess its therapeutic potential in immunological diseases and cancer
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