LRAT antibody
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Description
Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | lecithin retinol acyltransferase(phosphatidylcholine--retinol O-acyltransferase) (LRAT) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 26 kDa, 50-54 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O95237 |
| Gene ID | 9227 |
| Alias | Lecithin retinol acyltransferase,Phosphatidylcholine--retinol O-acyltransferase,LRAT |
| Background | Antibody anti-LRAT |
| Status | RUO |
| Note | Mol. Weight 26 kDa, 50-54 kDa |
Descripción
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