ADGRL3 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
ADGRL3 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab04829
Tested Applications
ELISA, WB, IP
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | latrophilin 3 (ADGRL3) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 139 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9HAR2 |
| Alias | ADGRL3,CL3,LEC3,CIRL3,LPHN3,latrophilin 3,calcium-independent receptor of alpha-latrotoxin 3,LEC3,Lectomedin-3,CL3,CIRL/latrophilin 3 |
| Background | Antibody anti-ADGRL3 |
| Status | RUO |
| Note | Mol. Weight 139 kDa |
Background
ADGRL3, also referred to as Latrophilin-3, is primarily expressed in the central nervous system and plays a pivotal role in neural circuit formation, synaptic development, and plasticity. Its interaction with neuronal ligands facilitates trans-synaptic adhesion, critical for the regulation of synaptic strength and maintenance of neural connectivity. ADGRL3 is implicated in neuropsychiatric and developmental disorders, with genetic mutations linked to conditions such as attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorders. It regulates intracellular signaling pathways involved in neuronal differentiation and synaptic maturation, underscoring its role in both developmental and functional aspects of the nervous system. Dysregulation of ADGRL3 can lead to altered neuronal communication, impacting behavior, cognition, and overall neurological health.
Productos relacionados
Latrophilin 3 / LPHN3 (ADGRL3) Antibody
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function…
Ver producto
Latrophilin 3 / LPHN3 (ADGRL3) Antibody
Latrophilin 3 / LPHN3 (ADGRL3) Antibody is a Rabbit Polyclonal against Latrophilin 3 / LPHN3 (ADGRL3).…
Ver producto
Latrophilin 3 / LPHN3 (ADGRL3) Antibody
Latrophilin 3 / LPHN3 (ADGRL3) Antibody is a Rabbit Polyclonal against Latrophilin 3 / LPHN3 (ADGRL3).…
Ver producto