LPCAT2 antibody

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Description
Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet-activating factor(PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine(lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine(PAF). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine(PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Also catalyzes the conversion of 1-acyl-sn-glycero-3-phosphocholine to 1,2-diacyl-sn-glycero-3-phosphocholine.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | lysophosphatidylcholine acyltransferase 2 (LPCAT2) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500-1:2000 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 53kd |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q7L5N7 |
Gene ID | 54947 |
Alias | Lysophosphatidylcholine acyltransferase 2 (LPC acyltransferase 2, LPCAT-2, LysoPC acyltransferase 2),1-acylglycerol-3-phosphate O-acyltransferase 11 (1-AGP acyltransferase 11, 1-AGPAT 11),1-acylglycerophosphocholine O-acyltransferase,1-alkenylglycerophosphocholine O-acyltransferase,1-alkylglycerophosphocholine O-acetyltransferase,Acetyl-CoA:lyso-platelet-activating factor acetyltransferase (Acetyl-CoA:lyso-PAF acetyltransferase, Lyso-PAF acetyltransferase, LysoPAFAT),Acyltransferase-like 1,Lysophosphatidic acid acyltransferase alpha (LPAAT-alpha),LPCAT2,AGPAT11,AYTL1 |
Background | Antibody anti-LPCAT2 |
Status | RUO |
Note | Mol. Weight 53 kDa |
Descripción
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LPCAT2 antibody
Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet-activating factor(PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine(lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine(PAF). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine(PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Also catalyzes the conversion of 1-acyl-sn-glycero-3-phosphocholine to 1,2-diacyl-sn-glycero-3-phosphocholine.
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