LBR antibody
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935106861
info@markelab.com
name
LBR antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04715
tested applications
ELISA, WB, IF, IP
Description
Anchors the lamina and the heterochromatin to the inner nuclear membrane.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | lamin B receptor (LBR) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 58 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q14739 |
| Gene ID | 3930 |
| Alias | Delta(14)-sterol reductase LBR (Delta-14-SR),3-beta-hydroxysterol Delta (14)-reductase,C-14 sterol reductase (C14SR),Integral nuclear envelope inner membrane protein,LMN2R,Lamin-B receptor,Sterol C14-reductase,LBR |
| Background | Antibody anti-LBR |
| Status | RUO |
| Note | Mol. Weight 58 kDa |
Descripción
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Lamin-B Receptor (LBR) Antibody
LBR Antibody is a Rabbit Polyclonal antibody against LBR. The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
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