anti- KPNA1 antibody

Descripción

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.

Características del producto

clonality

polyclonal

reactivity

human,mouse,rat

immunogen target

karyopherin alpha 1 (importin alpha 5)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IHC, IF

observerd MW

66 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

or code

KPNA1

alias

KPNA1,IPOA5, NPI-1, RCH2, SRP1, Importin, Importin subunit alpha-5, karyopherin subunit alpha 1

uniprot id

https://www.uniprot.org/uniprotkb/P52294

gene id

https://www.ncbi.nlm.nih.gov/gene/3836

note

This product is for research use only.

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