KLF10 antibody
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935106861
info@markelab.com
name
KLF10 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04597
tested applications
ELISA, WB, IF, IP
Description
Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis(By similarity). May play a role in the cell cycle regulation.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Kruppel-like factor 10 (KLF10) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 52 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q13118 |
| Gene ID | 7071 |
| Alias | Krueppel-like factor 10,EGR-alpha,Transforming growth factor-beta-inducible early growth response protein 1 (TGFB-inducible early growth response protein 1, TIEG-1),KLF10,TIEG,TIEG1 |
| Background | Antibody anti-KLF10 |
| Status | RUO |
| Note | Mol. Weight 52 kDa |
Descripción
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KLF10 antibody
Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis(By similarity). May play a role in the cell cycle regulation.
Ver Producto