MARF1 antibody
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Description
Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks(By similarity).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | KIAA0430 (MARF1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:1000; IP: 1:200-1:1000 ; IHC: 1:20-1:200; IF: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 192 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9Y4F3 |
| Gene ID | 9665 |
| Alias | Meiosis regulator and mRNA stability factor 1,Limkain-b1,Meiosis arrest female protein 1,MARF1,KIAA0430,LKAP |
| Background | Antibody anti-MARF1 |
| Status | RUO |
| Note | Mol. Weight 192 kDa |
Descripción
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