JMJD4 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | jumonji domain containing 4 (JMJD4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 48 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9H9V9 |
| Gene ID | 65094 |
| Alias | 2-oxoglutarate and iron-dependent oxygenase JMJD4,JmjC domain-containing protein 4,Jumonji domain-containing protein 4,Lysyl-hydroxylase JMJD4,JMJD4 |
| Background | Antibody anti-JMJD4 |
| Status | RUO |
| Note | Mol. Weight 48 kDa |
Related Products
JMJD4 antibody
Ver Producto
Jumonji Domain-Containing Protein 4 (JMJD4) Antibody
JMJD4 Antibody is a Rabbit Polyclonal Antibody against JMJD4.
Ver Producto
Jumonji Domain-Containing Protein 4 (JMJD4) Antibody
Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe (II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
Ver Producto