ITPKA antibody

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935106861
info@markelab.com
name
ITPKA antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04422
tested applications
ELISA, WB, IHC, IF, IP
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | inositol 1,4,5-trisphosphate 3-kinase A (ITPKA) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 51 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, IF, IP |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | P23677 |
Gene ID | 3706 |
Alias | Inositol-trisphosphate 3-kinase A,Inositol 1,4,5-trisphosphate 3-kinase A (IP3 3-kinase A, IP3K A, InsP 3-kinase A),ITPKA |
Background | Antibody anti-ITPKA |
Status | RUO |
Note | Mol. Weight 51 kDa |
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ITPKA regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1, 4, 5-trisphosphate to Ins (1, 3, 4, 5) P4. The activity of the inositol 1, 4, 5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region.
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