ITPA antibody

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935106861
info@markelab.com
name
ITPA antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04420
tested applications
ELISA, WB, IF, IHC, IP
Description
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate(ITP), deoxyinosine triphosphate(dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate(dHAPTP) and xanthosine 5'-triphosphate(XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy-and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | inosine triphosphatase(nucleoside triphosphate pyrophosphatase) (ITPA) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 22 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BY32 |
| Gene ID | 3704 |
| Alias | Inosine triphosphate pyrophosphatase (ITPase, Inosine triphosphatase),Non-canonical purine NTP pyrophosphatase,Non-standard purine NTP pyrophosphatase,Nucleoside-triphosphate diphosphatase,Nucleoside-triphosphate pyrophosphatase (NTPase),Putative oncogene protein hlc14-06-p,ITPA,C20orf37 |
| Background | Antibody anti-ITPA |
| Status | RUO |
| Note | Mol. Weight 22 kDa |
Descripción
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ITPA antibody
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate(ITP), deoxyinosine triphosphate(dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate(dHAPTP) and xanthosine 5'-triphosphate(XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy-and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
Ver Producto